Partial Dysautonomia

A partial dysautonomia could account for the warm dry feet (loss of sudomotor nerve), the gravity-dependent dusky skin (blood suffusion of the skin), the leg vein hyper-responsiveness to norepinephrine, the reduced galvanic responses, abnormal sweating of the extremities, the excessive orthostatic blood pooling, the tachycardia, and the reduced stroke volume seen in OI patients.