R. Daniel Beauchamp, MD

Chairman, Section of Surgical Sciences
Foshee Distinguished Professor of Surgery

BeauchampR. Daniel Beauchamp, MD, FACS, is the John Clinton Foshee Distinguished Professor of Surgery, Chairman of the Section of Surgical Sciences, and Surgeon-in-Chief of Vanderbilt University Hospital and has held these positions since July 2001. He also has joint appointments as professor in the departments of Cell and Developmental Biology and Cancer Biology. He also serves as Associate Director for Clinical/Translational Programs in the Vanderbilt-Ingram Cancer Center. Dr. Beauchamp joined the faculty of the Vanderbilt University Medical Center as Associate Professor in the Department of Surgery, Division of Surgical Oncology and Associate Professor of Cell Biology in December 1994. His ongoing institutional administrative responsibilities also include the Chair of the Perioperative Enterprise Committee, and service on the Perioperative Executive Committee, the VMG Executive Committee, the Medical School Executive Committee, the Clinical Enterprise Group, the Quality Council, the ELEVATE Steering Committee, and the Surgical Critical Care Steering Committee.

Dr. Beauchamp came to Vanderbilt from the University of Texas Medical Branch (UTMB), Galveston, Texas, where he was Associate Professor in the Department of Surgery and the Department of Human Biological Chemistry and Genetics. The activities of Dr. Beauchamp over the past decade support the Vanderbilt mission of education, patient care, and research. During his UTMB tenure Dr. Beauchamp served as an attending faculty member for the General Surgery Service, the Surgery Tumor Clinic, and the Surgical Intensive Care Unit. During his last four years there he chaired the Residency Review Committee for General Surgery. While at UTMB, Dr. Beauchamp was also director of the James E. Thompson Memorial Molecular Biology Laboratory for Surgical Research.

Here at Vanderbilt University, Dr. Beauchamp has a clinical practice focused in Surgical Oncology. He cares for patients with a broad spectrum of malignancies, including gastrointestinal tract cancers, breast cancer, melanoma and soft tissue sarcoma. Dr. Beauchamp participates in the multidiscliplinary GI Oncology clinic every Wednesday and holds clinic in the Vanderbilt Breast Center on Thursday mornings. He uses the clinical settings to teach residents and medical students, in a one-on-one setting and in small groups. In addition, he regularly leads an Evidence-based Medicine teaching session with the entire group of Surgical Residents and medical students on the GeneralSurgery Clerkship rotation.

In addition to clinical practice and administrative responsibilities, Dr. Beauchamp has a productive research laboratory. He spent two years (1987-1989) conducting basic growth factor research in the Department of Cell Biology at Vanderbilt under the direction of Dr. Harold Moses after completion of his residency at UTMB. After two years in Dr. Moses' laboratory Dr. Beauchamp returned to UTMB as assistant professor in the departments of Surgery and Human Biological Chemistry and Genetics. His research fellowship was funded by the National Cancer Institute in the form of a Physician Scientist Award which supported his work for 5 years post-residency. Since completion of his Surgical residency, Dr. Beauchamp's research work has maintained and has been continually funded by the NIH and other extramural funding agencies. He currently has two active R01 grants from the NIH, and is a project leader for the Gastrointestinal Cancer Specialized Program of Research Excellence (SPORE) Grant. Dr. Beauchamp's primary area of interest has been in colorectal carcinogenesis and in the development of novel biomarkers and therapeutic strategies in colorectal and other alimentary tract malignancies. Recently published work from Dr. Beauchamp's laboratory has identified a tight junction protein, Claudin-1, to have a previously unknown role in the promotion of invasive and metastatic behavior in colon cancer cells. He is also using cutting edge DNA microarray and proteomic technology to identify novel biomarkers and therapeutic targets in human colorectal cancer samples collected from the Vanderbilt University surgical practice. In addition to the basic cancer research Dr. Beauchamp has been a participant in the Eastern Cooperative Oncology Group, and works in collaboration with his Medical Oncology and Radiation Oncology colleagues to accrue cancer patients to approved clinical trials.

Dr. Beauchamp is active in several national surgical and scientific organizations. He is a member of the Society of University Surgeons where he served as President in 1999, and was on the Executive Council for 10 years. He is also a member of the American Society of Clinical Investigation, the Society for Surgical Oncology, the Association for Academic Surgeons, the Southern Surgical Association, the American Surgical Association, the Society for Surgery of the Alimentary Tract, the American Association for Cancer Reseach, the American Society of Clinical Oncology, the American Gastroenterology Association, the Halsted Society and the American Society for Cell Biology, among others. He serves or has served on the Editorial Boards of the Journal of Parenteral and Enteral Nutrition, the Journal of Surgical Research, Surgery, the Journal of the American College of Surgeons, Contemporary Surgery, and the Annals of Surgical Oncology. He is also an Associate Editor for the Sabiston Textbook of Surgery.