The Vanderbilt Institute of Chemical Biology presents Dr. Ryan Altman, University of Kansas: ""Fluorination Strategies for Synthetic Methodology and Medicinal Chemistry"
Key Lecture Points
• New synthetic methods enable access to fluorinated substructures commonly found biological probes and therapeutic candidates
• A Pd-based catalyst system enables an undirected para-selective C–H functionalization reaction from a simple aromatic substrate
• Fluorinated ethers and ethermimetics perturb distribution, metabolism, and pharmacokinetic properties of neurotherapeutics