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  • 1/31/2019
    11:50 am - 12:55 pm
    VICB Seminar, Ryan Altman, University of Kansas

    The Vanderbilt Institute of Chemical Biology presents Dr. Ryan Altman, University of Kansas: ""Fluorination Strategies for Synthetic Methodology and Medicinal Chemistry"

    Key Lecture Points

    • New synthetic methods enable access to fluorinated substructures commonly found biological probes and therapeutic candidates
    • A Pd-based catalyst system enables an undirected para-selective C–H functionalization reaction from a simple aromatic substrate
    • Fluorinated ethers and ethermimetics perturb distribution, metabolism, and pharmacokinetic properties of neurotherapeutics